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The FHIR standard specifies the specific format of errors responses and API outcomes.

The Operation outcomes are sets of error, warning and information messages that provide detailed information about the outcome of an attempted system operation. They are provided as a direct system response or component of one and provide information about the outcome of the operation.

More information can be found here: https://www.hl7.org/fhir/STU3/operationoutcome.html

The Python Django provides the possibility to create the custom exception handling which can be used to handle the specific API exceptions. In order to add custom exception handling the application configuration for REST need to be changed. 

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